What is the accuracy of the Padua Prognostic Score for predicting postoperative CD in patients undergoing restorative proctocolectomy

What is known

- The PPSC integrates preoperative perianal abscess or fistula, rectal sparing, terminal ileum involvement, skip lesions, and histological diagnosis of indeterminate or Crohn's colitis on the operative specimen. ¹ - In the validation cohort of 138 patients (127 ulcerative colitis, 11 indeterminate colitis), 6 developed a new postoperative diagnosis of Crohn's disease. ¹ - The clinical-only version of the PPSC had lower accuracy for predicting Crohn's colitis diagnosis after surgery than the full score. ¹

What is unknown / caveats

- Single retrospective validation study from one institution - Only 6 postoperative Crohn's diagnoses, limiting reliable analysis - The small number of postoperative Crohn's disease diagnoses prevented meaningful analysis of outcomes in those patients.

## References

1. Angriman I, Colangelo A, Mescoli C, Fassan M, D'Incà R, Savarino E, Pucciarelli S, Bardini R, Ruffolo C, Scarpa M. Validation of the Padova Prognostic Score for Colitis in Predicting Long-Term Outcome After Restorative Proctocolectomy. Front Surg. 2022;9:911044. PMID: 35959125.

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